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RNAi Global Initiative
Dharmacon Announces the creation of the First Genome-wide, RNAi Global Initiative

Recently, Dharmacon announced the formation of the first genome-wide initiative for RNAi.  The reason for the Initiative is to accelerate the scientific progress made possible by the availability of the first complete siRNA library to target genes across the entire human genome. This is a great milestone in the genomics realm since this is the first time, ever, that such an endevor has been undertaken.

The spirit of the Initiative is to bring together some of the largest names in the genomics research field and foster an atmosphere of co-operation. This will be acheived by conducting analyses in relevant cellular assays across different disease states with the same library of inhibitors and derive multidimensional relationships of gene function in disease.

Some of the key members of the RNAi Global Initiative are University of Texas Southwestern Medical Center, Cambridge University, Yale University, Cancer Research UK (CRUK), University of Texas M.D. Anderson Cancer Center, German Cancer Research Center, Netherlands Cancer Institute, University of Toronto and University of Edinburgh Medical School, as well as others.

Dharmacon’s Role in The Initiative
Dharmacon is providing each partner with the siARRAY® Human Genome siRNA Library which is a collection of preselected groups of SMARTselection™ designed siRNA reagents–individual duplexes or SMARTpool® reagents targeting all unique human genes in the NCBI RefSeq database–conveniently arranged in 96-well plates for easy storage and rapid preparation.  The Human siGENOME™ siRNA Library is designed to accelerate functional genomics research and to make siRNA SMARTselection™ technology accessible to ALL researchers for detailed analysis of gene families and metabolic pathways.

The vision of the Global Initiative are to assist in the advancement of basic biomedical research and speed drug discovery by accelerating the utility of the revolutionary research tool represented by the complete human whole genome siRNA library.

Visit the RNAi Global Initiative website for more information.