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The Dharmacon RNA Learning Center is an online resource containing pertinent information on all things related to RNAi. Whether you are 'New to RNAi' or experienced in the field, you are sure to find something to pique your interest.
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New to RNAi
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In vivo RNAi: Biodistribution, Delivery,
and Applications
In vivo RNAi has been used for target validation
studies in animal disease models . . . [more]
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Technical Notes
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Using Mimics and Inhibitors for
microRNA (miRNA) Functional Analysis
MicroRNAs (miRNAs) are naturally occurring short RNA molecules
of about 22 nucleotide (nt) long that regulate gene expression . . . [more]
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Applications
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High Content Analysis Using Targeted RNAi-Mediated Gene Knockdown: Integrating the Cellomics® ArrayScan® HCS Reader and the Dharmacon siARRAY® Cell Cycle siRNA Library [more]
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Tech.edu
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Off-Target Effects: Disturbing the Silence of RNA interference (RNAi)
Off-target effects occur when an siRNA is processed by the RNA-Induced Silencing Complex (RISC) and down-regulates unintended targets . . . [more]
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Dharmacon in the Real World
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Recently, a question was posed concerning how one might go about discerning the difference between a true hit and a false positive . . . [more]
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Two recent independent studies demonstrated, in a clinically relevant setting, the utility of siRNA-mediated silencing in the identification of novel targets for alternative HIV therapies . . .
[more]
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Setting the Standard - The Genome-wide, RNAi Global
Initiative
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Since the inaugural meeting held in October 2005 in Boston, the RNAi
Global Initiative has expanded to embrace new members representing the
Fox Chase Cancer Center, Harvard Medical School, Stanford University and the
Vrije University Medical Center. The group represents a unique partnership
among labs from leading institutions with international reputations in
biomedical research.
[more]
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©2006 Dharmacon, Inc. All rights reserved.
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ON-TARGETplus™ siRNA - The new
standard for silencing specificity
Reducing off-target effects is crucial to RNAi success. Dharmacon is
advancing siRNA technology to decrease false positives for increased
accuracy and reliability.
[learn more]
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Special Introductory Pricing for
ON-TARGETplus siRNA!
Save up to 15% depending on size and configuration.
[Details here]
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Which controls do you use in your RNAi experiments? Please
take a minute to answer these 5
questions.
[here]
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Press Release:
04/04/2006:
FOX CHASE CANCER CENTER Joins DHARMACON and International Research Institutes as Newest Member of the Genome-Wide RNAi GLOBAL INITIATIVE [more]
Events:
5/21-5/25
ASM - Microbiology
Orlando FL
6/19-6/21
Beyond Genomes
San Francisco CA
6/20-6/25
RNA Society Annual Meeting
Seattle WA
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