In this issue

News
Two RNAi Research Teams Collaborate
The Life Science Research (LSR) teams in Lafayette, Colorado, and Huntsville, Alabama, are working together to advance the application of RNA-interference (RNAi) in biomedical research as well as to integrate the complementary RNAi platforms...[more]

Product Spotlight
Bringing on-target specificity to genome-wide siRNA.
Announcing the availability of ON-TARGETplus siRNA reagents as a whole human genome siRNA library! ... [more]

Making a Difference
Targeted Accell siRNA to KLF6-SV1 affects tumor progression in a mouse model of ovarian cancer
Mechanistic insight now provided by Martignetti and co-workers using a chemically modified siRNA (Dharmacon Accell) to allow in vivo delivery has established KLF6-SV1 as being a novel anti-apoptotic protein, importantly, functioning independent of a tumor cells p53 status, which suggests its potential as a novel target for anticancer therapy either as a single agent or combined with the current gold standard platinum-based drugs...[more]

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