The most complete, proven solution for reducing off-target effects up to 90% - for fewer false positives
Market-leading Thermo Scientific Dharmacon ON-TARGETplus siRNA reagents deliver the highest-confidence RNAi results available by combining guaranteed silencing with unmatched strategies for greater target specificity.
The only dual-strand modification pattern available; superior to single-strand modifications for its proven ability to reduce off-targets caused by both strands.
Cutting-edge bioinformatics apply seed-region analysis to reduce miRNA-like off-target activity.
SMARTpool technology reduces the effective concentration of each siRNA for even greater target specificity.
Find out more about ON-TARGETplus design.