RNAi Therapeutic Development Services
Successful development of RNAi therapeutics requires expertise in the design and synthesis of highly functional RNAi reagents, novel formulations and strategies for delivery, and innovations in medicinal chemistry that enhance stability, specificity and biodistribution.
We provide seamless integration of these reagents with state-of-the-art technologies including high-throughput and high-content screening capabilities, novel delivery methods, and bioinformatics tools for data analysis and interpretation.
Through access to a broad portfolio of IP, the Thermo Scientific life science team offers the most complete services currently available to ensure quality data for RNAi therapeutic programs.
Core divisional elements include:
- Scientific experts recognized for contributions in the fields of RNAi, nucleic acid chemistry, and therapeutic delivery
- Leading-edge RNAi reagents:
- Potent siRNA and microRNA reagents designed using validated bioinformatics strategies
- Proprietary chemical modification patterns that enhance stability and specificity of nucleic acids used in RNAi-mediated gene knockdown
- Unique delivery strategies for user-defined cellular/tissue uptake and biodistribution
- Preclinical-scale synthesis for phase trials
- Access to early (2002-2003) intellectual property coverage in the field of RNAi that includes divisional filings from Dharmacon patent applications