Dharmacon - RNA Pricing Information

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Part of Thermo Fisher Scientific

Custom RNA

RNA Pricing Information

RNA • Modifications • Purification • Deprotect/Desalt • Express Synthesis

RNA Pricing

RNA Oligos are priced per base, plus a set-up charge for each oligo. Both the set-up charge and per base fees are based on the scale and type of RNA being manufactured. Refer to the table below for current pricing.

Price Per Base
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
Length Available (Bases):	10-40	2-65	2-80	2-35
RNA	$6.10	$7.75	$12.90	$17.00
2'-OMe	$7.75	$9.80	$14.45	$18.50
2'-Deoxy	$5.15	$6.20	$9.30	$14.45

Modifications

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We are continually developing the incorporation of modifications and minor bases. If a modification that you desire is not listed below, please inquire. It may be available as a product under development or we may be able to add it to our list of R&D projects. Your feedback will assist Dharmacon in ensuring that the modifications which we offer best address our customers' needs.

Internal Modifications
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
2,6-Diaminopurine	$90.00	$90.00	$100.00	$125.00
2'-Amino-butyryl-pyrene-uridine	N/A	$125.00	$140.00	$175.00
2'-Amino-uridine	N/A	$75.00	$85.00	$110.00
2'-Deoxy-uridine	$30.00	$30.00	$40.00	$55.00
2'-Fluoro-cytidine	$50.00	$50.00	$60.00	$75.00
2'-Fluoro-uridine	$50.00	$50.00	$60.00	$75.00
2-Aminopurine	N/A	$90.00	$100.00	$125.00
4-Thio-uridine	N/A	$125.00	$140.00	$175.00
5-Bromo-uridine	$75.00	$75.00	$85.00	$110.00
5-Fluoro-cytidine	N/A	$125.00	$140.00	$175.00
5-Fluoro-uridine	$75.00	$75.00	$85.00	$110.00
5-Iodo-uridine	$75.00	$75.00	$85.00	$110.00
5-Methyl-cytidine	N/A	$75.00	$85.00	$110.00
2'-Amino-cytidine	N/A	$90.00	$100.00	$125.00
Inosine	$30.00	$30.00	$40.00	$55.00
N3-Methyl-uridine	$75.00	$75.00	$85.00	$110.00
Pseudouridine	$90.00	$90.00	$100.00	$125.00
Purine ribonucleoside	$75.00	$75.00	$85.00	$110.00
Ribo-thymidine	$75.00	$75.00	$85.00	$110.00
5-Amino-allyl-uridine	N/A	$125.00	$140.00	$175.00
Deoxy-abasic	N/A	$90.00	$100.00	$125.00
N6, N6-Dimethyl-adenosine	N/A	$90.00	$100.00	$125.00
X (Dharmacon Approval Required)	N/A	$500.00	$500.00	$500.00

5' Modifications
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
5'-TAMRA-hexyl linker	N/A	$190.00	$225.00	$275.00
5'-Phosphate	$50.00	$50.00	$60.00	$75.00
5'-Amino, (6-carbon) linker	$75.00	$75.00	$85.00	$110.00
5'-Biotin	$90.00	$90.00	$100.00	$125.00
5'-Fluorescein	$90.00	$90.00	$100.00	$125.00
5'-Tetrachloro-fluorescein	N/A	$90.00	$100.00	$125.00
5'-Pyrene	N/A	$150.00	$180.00	$225.00
5'-Thiol	N/A	$125.00	$140.00	$175.00
5'-Amino, (12 Carbon) linker	N/A	$90.00	$100.00	$125.00
5'-Photocleavable Biotin	N/A	$175.00	$225.00	$250.00
5'-Dabcyl	N/A	$125.00	$140.00	$175.00
5'-Cholesterol	N/A	$140.00	$160.00	$200.00
5'-DY547 (Cy3™ alternate)	$125.00	$125.00	$140.00	$175.00

Degenerate Bases
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
rN	N/A	$50.00 $7.50 / addl.	$60.00 $12.50 / addl.	$75.00 $16.50 / addl.
rW	N/A	$50.00 $7.50 / addl.	$60.00 $12.50 / addl.	$75.00 $16.50 / addl.
rS	N/A	$50.00 $7.50 / addl.	$60.00 $12.50 / addl.	$75.00 $16.50 / addl.
dN	N/A	$50.00 $6.00 / addl.	$60.00 $9.00 / addl.	$75.00 $14.00 / addl.
dW	N/A	$50.00 $6.00 / addl.	$60.00 $9.00 / addl.	$75.00 $14.00 / addl.
dS	N/A	$50.00 $6.00 / addl.	$60.00 $9.00 / addl.	$75.00 $14.00 / addl.
mN	N/A	$50.00 $9.50 / addl.	$60.00 $14.00 / addl.	$75.00 $18.00 / addl.

3' Modifications
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
3'-Biotin	N/A	$140.00	$160.00	$200.00
3'-Inverted deoxythymidine	N/A	$50.00	$60.00	$75.00
3'-Puromycin	N/A	$50.00	$60.00	$75.00
3' Terminal dideoxy-cytidine	N/A	$75.00	$85.00	$110.00
3'-TAMRA	N/A	$190.00	$225.00	$275.00
3'-Fluorescein	N/A	$90.00	$100.00	$125.00
3' Terminal deoxy-guanosine	N/A	$75.00	$85.00	$110.00
3'-Cholesterol	N/A	$140.00	$160.00	$200.00
3'-Amino Modifier (6 atom)	N/A	$50.00	$60.00	$75.00
3'-DY547 (Cy3™ alternate)	N/A	$290.00	$350.00	$425.00

Phosphorothioate Modifications
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
Phosphorothioate	$25.00 $5.00 / addl.	$25.00 $5.00 / addl.	$28.00 $7.00 / addl.	$30.00 $10.00 / addl.

Other Modifications
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
18-Atom spacer (Hexaethylene glycol)	$30.00	$30.00	$40.00	$55.00
3-Carbon linker	$30.00	$30.00	$40.00	$55.00
9-Atom spacer	$30.00	$30.00	$40.00	$55.00

Purifications

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PAGE Purification (Please allow 4 additional days for processing)
Synthesis Scales:	0.05 µmol	0.2 µmol	0.4 µmol	1.0 µmol
	$97.00 (10-40 bases)	$125.00 (2-34 bases)	$150.00 (2-34 bases)	$175.00 (2-19 bases)
		$150.00 (35-45 bases)	$175.00 (35-45 bases)	$225.00 (20-30 bases)
		$175.00 (46+ bases)	$200.00 (46+ bases)	$250.00 (31+ bases)

2'-Deprotection & Desalting

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Deprotection and Desalting (Please allow additional time for processing, as indicated)
Price per Oligo	Extra Days
$60.00	1 (Per Order)

Express Synthesis

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Express Delivery Options
(Based on availability when received by 1:00 pm MST)

Service Price Per Oligo

24 Hour $75.00

48 Hour $50.00

72 Hour $20.00

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