RNA Pricing & Modifications
RNA • Modifications • Purification • Deprotect/Desalt • Express Synthesis
RNA Pricing
RNA Oligos are priced per base, plus a set-up charge for each oligo. Both the set-up charge and per base fees are based on the scale and type of RNA being manufactured. Refer to the table below for current pricing.
Price Per Base
Synthesis Scales:0.05 µmol0.2 µmol0.4 µmol1.0 µmol
Length Available (Bases):10-402-672-802-35
RNA$6.10$7.75$12.90$17.00
2'-OMe$7.75$9.80$14.45$18.50
2'-Deoxy$5.15$6.20$9.30$14.45
Modifications Top
We are continually developing the incorporation of modifications and minor bases. If a modification that you desire is not listed below, please inquire. It may be available as a product under development or we may be able to add it to our list of R&D projects. Your feedback will assist Dharmacon in ensuring that the modifications which we offer best address our customers' needs.
Internal Modifications
Synthesis Scales:0.05 µmol0.2 µmol0.4 µmol1.0 µmol
2,6-Diaminopurine$90.00$90.00$100.00$125.00
2'-Amino-butyryl-pyrene-uridineN/A$125.00$140.00$175.00
2'-Amino-uridineN/A$75.00$85.00$110.00
2'-Deoxy-uridine$30.00$30.00$40.00$55.00
2'-Fluoro-cytidine$50.00$50.00$60.00$75.00
2'-Fluoro-uridine$50.00$50.00$60.00$75.00
2-AminopurineN/A$90.00$100.00$125.00
4-Thio-uridineN/A$125.00$140.00$175.00
5-Bromo-uridine$75.00$75.00$85.00$110.00
5-Fluoro-cytidineN/A$125.00$140.00$175.00
5-Fluoro-uridine$75.00$75.00$85.00$110.00
5-Iodo-uridine$75.00$75.00$85.00$110.00
5-Methyl-cytidineN/A$75.00$85.00$110.00
2'-Amino-cytidineN/A$90.00$100.00$125.00
Inosine$30.00$30.00$40.00$55.00
N3-Methyl-uridine$75.00$75.00$85.00$110.00
Pseudouridine$90.00$90.00$100.00$125.00
Purine ribonucleoside$75.00$75.00$85.00$110.00
Ribo-thymidine$75.00$75.00$85.00$110.00
5-Amino-allyl-uridineN/A$125.00$140.00$175.00
Deoxy-abasicN/A$90.00$100.00$125.00
N6, N6-Dimethyl-adenosineN/A$90.00$100.00$125.00
X (Dharmacon Approval Required)N/A$500.00$500.00$500.00

5' Modifications
Synthesis Scales:0.05 µmol0.2 µmol0.4 µmol1.0 µmol
5'-TAMRA-hexyl linkerN/A$190.00$225.00$275.00
5'-Phosphate$50.00$50.00$60.00$75.00
5'-Amino, (6-carbon) linker$75.00$75.00$85.00$110.00
5'-Biotin$90.00$90.00$100.00$125.00
5'-Fluorescein$90.00$90.00$100.00$125.00
5'-Tetrachloro-fluoresceinN/A$90.00$100.00$125.00
5'-PyreneN/A$150.00$180.00$225.00
5'-ThiolN/A$125.00$140.00$175.00
New Item 5'-Amino, (12 Carbon) linkerN/A$90.00$100.00$125.00
5'-Photocleavable BiotinN/A$175.00$225.00$250.00
5'-DabcylN/A$125.00$140.00$175.00
5'-CholesterolN/A$140.00$160.00$200.00
New Item 5'-DY547 (Cy3™ alternate)$125.00$125.00$140.00$175.00

Degenerate Bases
Synthesis Scales:0.05 µmol0.2 µmol0.4 µmol1.0 µmol
rNN/A$50.00
$7.50 / addl.		$60.00
$12.50 / addl.		$75.00
$16.50 / addl.
rWN/A$50.00
$7.50 / addl.		$60.00
$12.50 / addl.		$75.00
$16.50 / addl.
rSN/A$50.00
$7.50 / addl.		$60.00
$12.50 / addl.		$75.00
$16.50 / addl.
dNN/A$50.00
$6.00 / addl.		$60.00
$9.00 / addl.		$75.00
$14.00 / addl.
dWN/A$50.00
$6.00 / addl.		$60.00
$9.00 / addl.		$75.00
$14.00 / addl.
dSN/A$50.00
$6.00 / addl.		$60.00
$9.00 / addl.		$75.00
$14.00 / addl.
mNN/A$50.00
$9.50 / addl.		$60.00
$14.00 / addl.		$75.00
$18.00 / addl.

3' Modifications
Synthesis Scales:0.05 µmol0.2 µmol0.4 µmol1.0 µmol
3'-BiotinN/A$140.00$160.00$200.00
3'-Inverted deoxythymidineN/A$50.00$60.00$75.00
3'-PuromycinN/A$50.00$60.00$75.00
3' Terminal dideoxy-cytidineN/A$75.00$85.00$110.00
3'-TAMRAN/A$190.00$225.00$275.00
3'-FluoresceinN/A$90.00$100.00$125.00
3' Terminal deoxy-guanosineN/A$75.00$85.00$110.00
3'-CholesterolN/A$140.00$160.00$200.00
New Item 3'-Amino Modifier (6 atom)N/A$50.00$60.00$75.00
New Item 3'-DY547 (Cy3™ alternate)N/A$290.00$350.00$425.00

Phosphorothioate Modifications
Synthesis Scales:0.05 µmol0.2 µmol0.4 µmol1.0 µmol
Phosphorothioate$25.00
$5.00 / addl.		$25.00
$5.00 / addl.		$28.00
$7.00 / addl.		$30.00
$10.00 / addl.

Other Modifications
Synthesis Scales:0.05 µmol0.2 µmol0.4 µmol1.0 µmol
18-Atom spacer (Hexaethylene glycol)$30.00$30.00$40.00$55.00
3-Carbon linker$30.00$30.00$40.00$55.00
9-Atom spacer$30.00$30.00$40.00$55.00
Purifications Top
PAGE Purification
(Please allow 4 additional days for processing)
Synthesis Scales: 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol

97
(10-40 bases) 		125
(2-34 bases) 		150
(2-34 bases) 		175
(2-19 bases)


150
(35-45 bases) 		175
(35-45 bases) 		225
(20-30 bases)


175
(46+ bases) 		200
(46+ bases) 		250
(31+ bases)
2'-Deprotection & Desalting Top
Deprotection and Desalting
(Please allow additional time for processing, as indicated)
Price per Oligo Extra Days
60 1 (Per Order)
Express Synthesis Top

Express Delivery Options
(Based on availability when received by 1:00 pm MST)
Service Price Per Oligo
24 Hour 75
48 Hour 50
72 Hour 20

 
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