As technology leaders in the field of RNAi research, Dharmacon makes this web-based tool available to the scientific community in consideration of the on-going efforts to develop intelligent and effective tools for selecting viable siRNA candidates and advancing the rational design of such. The algorithm is made available in support of published work.

However, Dharmacon and the creators of this tool make no claims as to the predictive value of this algorithm, whether utilized as a single parameter or in conjunction with additional parameters, in the assessment of potential siRNA functionality, specificity or potency, nor do we guarantee any experimental results obtained through the incorporated use of this algorithm.