The siDESIGN^® Center is an advanced, user-friendly siRNA design tool, which significantly improves the likelihood of identifying functional siRNA.

One-of-a-kind options are now available to enhance target specificity and adapt siRNA designs for more sophisticated experimental design.

Click the icon for context-specific Help from our online User Guide.

siDESIGN® Center Brochure

For guaranteed gene silencing, search for your gene in the siGENOME^® collection of pre-designed human, mouse, and rat siRNA reagents.

Step 1: Select an Identifier Type:

Identifier Type:

Enter Accession:

Step 2: Select desired region(s) for siRNA design:

5' UTRORF3' UTR

Step 3: Enter minimum and maximum G/C percentage, or accept the default (recommended)

Minimum GC%:

Maximum GC%:

Step 4: Choose BLAST options.

No BLASTBLAST Database

Step 5: Click Design to generate a list of candidate siRNA sequences.